
Pharmaceuticals & Biotechnology
VUP provides intermediates and services for pharma and biotech, ensuring purity and compliance with innovative chemistry.
Key Applications

API Synthesis & Pharmaceutical Intermediates
Sourcing high-purity, reliably supplied raw materials and intermediates is crucial for Active Pharmaceutical Ingredient (API) manufacturing.

Biomedical Materials & Device Coatings
Developing advanced medical devices and therapies often requires specialized biocompatible materials with unique functional properties.

Diagnostic Aids & Healthcare Products
Reliable and safe consumable materials are essential for routine diagnostic procedures in healthcare settings.

Drug Discovery & Research Chemicals
Researchers require access to specialized, high-purity chemicals and reagents for target identification, screening, and preclinical studies.
Industry Challenges
Discover the unique challenges faced by Pharmaceuticals & Biotechnology and how VUP Solutions can help overcome them.
API Synthesis & Pharmaceutical Intermediates
Challenge:
Sourcing high-purity, reliably supplied raw materials and intermediates is crucial for Active Pharmaceutical Ingredient (API) manufacturing.
VUP Solutions:
We specialize in the production of TEMPO (CAS 2564-83-2) and related nitroxide radicals, which serve as versatile catalysts, antioxidants, and raw materials. VUP's Custom Synthesis service provides tailored production of other complex organic intermediates needed for drug development pipelines, backed by robust quality control.

Relevant Products
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TEMPO (2,2,6,6-Tetramethylpiperidin-1-oxyl)
A highly versatile and stable nitroxyl radical, renowned for its utility as a catalyst in selective organic oxidations and as a mediator in controlled radical polymerization (NMP). VUP produces high-purity TEMPO at pilot scale.
Key Properties

4-Hydroxy-TEMPO (TEMPOL / H-TEMPO)
A key functionalized derivative of TEMPO featuring both a stable nitroxyl radical and reactive hydroxyl group. Serves as a versatile antioxidant, catalyst, spin label, and crucial intermediate for synthesizing specialty chemicals.
Key Properties
Relevant Services
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Research & Development
VUP's R&D division solves complex chemistry challenges across diverse industries.With 70+ years of chemical expertise, we transform ideas into viable technological solutions tailored to your needs.
Accreditations

Accredited Analytical, Technical-Safety & Environmental Services
The ATBEL (Analytical, Technical-Safety, and Environmental Laboratories) division is a specialized testing center within VUP, a.s., providing expert analytical services to both internal R&D projects and external partners. We deliver reliable, accredited results under SNAS Certificate No. S-118 (ISO/IEC 17025) and ISO 9001, ensuring the highest standards of quality and precision. Our services are led by division head Ing. Ľudovít Žiak, PhD.
Accreditations
Biomedical Materials & Device Coatings
Challenge:
Developing advanced medical devices and therapies often requires specialized biocompatible materials with unique functional properties.
VUP Solutions:
VUP is the unique global producer of O,O'-Bis(3-aminopropyl)polyethyleneglycol (DAPEG), a high-value intermediate used to create lubricious, hydrophilic coatings for vascular intervention devices and other surgical applications. Building on this, we have developed pilot capabilities for PEG-diacrylamide (PEGDAA), a derivative with significant potential in tissue engineering, 3D bioprinting, and drug delivery systems. Our R&D team actively collaborates with partners like DSM Biomedical in this area.

Relevant Services
View all servicesDiagnostic Aids & Healthcare Products
Challenge:
Reliable and safe consumable materials are essential for routine diagnostic procedures in healthcare settings.
VUP Solutions:
We manufacture high-quality diagnostic gels, including GELSON for sonography and EV GEL for ECG/EEG examinations. These products are formulated using safe, dermatology/cosmetic-grade raw materials, are alcohol-free, non-irritating, and meet relevant health standards (Gelson holds a MoH SK health certificate). VUP also produces other fine chemicals and products for healthcare applications.

Relevant Services
View all servicesDrug Discovery & Research Chemicals
Challenge:
Researchers require access to specialized, high-purity chemicals and reagents for target identification, screening, and preclinical studies.
VUP Solutions:
Our TEMPO derivatives serve as important tools (antioxidants, spin labels) in pharmaceutical research. VUP also produces unique laboratory chemicals specifically for medical applications and offers Custom Synthesis services to provide researchers with novel compounds or specific intermediates needed for their discovery programs.

Relevant Products
View all products
TEMPO (2,2,6,6-Tetramethylpiperidin-1-oxyl)
A highly versatile and stable nitroxyl radical, renowned for its utility as a catalyst in selective organic oxidations and as a mediator in controlled radical polymerization (NMP). VUP produces high-purity TEMPO at pilot scale.
Key Properties

4-Hydroxy-TEMPO (TEMPOL / H-TEMPO)
A key functionalized derivative of TEMPO featuring both a stable nitroxyl radical and reactive hydroxyl group. Serves as a versatile antioxidant, catalyst, spin label, and crucial intermediate for synthesizing specialty chemicals.
Key Properties
Relevant Services
View all services
Research & Development
VUP's R&D division solves complex chemistry challenges across diverse industries.With 70+ years of chemical expertise, we transform ideas into viable technological solutions tailored to your needs.
Accreditations

Accredited Analytical, Technical-Safety & Environmental Services
The ATBEL (Analytical, Technical-Safety, and Environmental Laboratories) division is a specialized testing center within VUP, a.s., providing expert analytical services to both internal R&D projects and external partners. We deliver reliable, accredited results under SNAS Certificate No. S-118 (ISO/IEC 17025) and ISO 9001, ensuring the highest standards of quality and precision. Our services are led by division head Ing. Ľudovít Žiak, PhD.
Accreditations
Featured VUP Products
Explore our core portfolio of chemical intermediates and solutions for this industry

TEMPO (2,2,6,6-Tetramethylpiperidin-1-oxyl)
A highly versatile and stable nitroxyl radical, renowned for its utility as a catalyst in selective organic oxidations and as a mediator in controlled radical polymerization (NMP). VUP produces high-purity TEMPO at pilot scale.
Key Properties

4-Hydroxy-TEMPO (TEMPOL / H-TEMPO)
A key functionalized derivative of TEMPO featuring both a stable nitroxyl radical and reactive hydroxyl group. Serves as a versatile antioxidant, catalyst, spin label, and crucial intermediate for synthesizing specialty chemicals.
